Research Article, J Virol Antivir Res Vol: 2 Issue: 4
Prevalence of Hepatitis Virus and HBV/HCV Interactions in Opiate Addict Subjects
Fabio Curcio1* and Clara Baldassarre2 |
1Centro Clinico Farmacodipendenze, Italy |
2Director Centro Clinico Farmacodipendenze, Italy |
Corresponding author : Fabio Curcio Via Ferdinando Russo, 29 80123 Napoli, Italy Tel: +39 3356744071; Fax: +39 081 2548109 E-mail: itinerari2008@alice.it |
Received: August 11, 2013 Accepted: December 10, 2013 Published: December 13, 2013 |
Citation: Curcio F, Baldassarre C (2013) Prevalence of Hepatitis Virus and HBV/HCV Interactions in Opiate Addict Subjects. J Virol Antivir Res 2:4. doi:10.4172/2324-8955.1000115 |
Abstract
Prevalence of Hepatitis Virus and HBV/HCV Interactions in Opiate Addict Subjects
Aims of the study were: 1) the assessment of the prevalence of HBV, HCV and HDV infections in opiate addict subjects; 2) the study of the viral interaction in vivo. Method: The study evaluated HBV and HCV infections in 1682 subjects assisted from 1990 to 2010. Outcomes: In 2010 the prevalence of HBV infection was of 42.3%; the number of HBs Ag carrier subjects was of 4,4%. HCV infection prevalence rose of 60.4%. The prevalence of the co-infection HBV/HCV was of 32.0%; during the co-infection phase, HBV infection spread earlier with a 2.8 higher probability than HCV infection. The RNA of HCV virus was positive in 25.9% of the cases of HBsAg carrier subjects. The RNA of HCV resulted to be positive among HBV infected subjects compared to HBV carrier subjects with O.R. 10.47.