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+44 28 3718 0055Advanced Biomedical Research and Innovation
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Amin Ahmadi Author
Subjects of specialization
Affiliation
Adolescent and Pediatric Gynecology, Anorexia Nervosa, Biochemistry of Reproductive Science, Biodiversity Management, Biodiversity and Conservation
Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
Biography
Previously, he was a Senior Editor and one of the launch editors at Nature Communications. He obtained his PhD from the University of Leicester, UK, in organic chemistry, and undertook postdoctoral work at The Australian National University.
Publications
Short Communication Open Access
Transplantation of mouse induced pluripotent stem cell-derived podocytes in a mouse model of membranous nephropathy attenuates proteinuria
Author(s): Reza Moghadasali, Amin Ahmadi, Hossein Baharvand and Nasser Aghdami
Injury to podocytes is a principle cause for initiation and progression of both immune and non-immune mediated glomerular diseases (GD) that result in proteinuria. Current advances in regenerative medicine shed light on the potential for cell-based therapy to treat several of these disorders. Thus, there is hope that generation and transplantation of podocytes from induced pluripotent stem cells (iPSCs) could potentially provide a curative treatment for glomerulonephritis caused by podocyte injury and loss. In this study, mouse model of membranous nephropathy (MN) was carried out with intravenous administration of anti-podocyte antibody (APA) after subcutaneous pre-immunization. iPSCs were derived from induced anti-podocyte nephropathy (APN) mouse tail-tip fibroblasts (TTFs) by retroviral ... view more»
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