Commentary, J Nanomater Mol Nanotechnol Vol: 4 Issue: 3
Zinc Ferrite Nanoparticles as Highly Effective Magnetic Resonance Imaging Contrast Agents with Emphasis on Atherosclerosis
Rajneesh Chaudhary, Rupinder K Kanwar and Jagat R Kanwar* | |
Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research(NLIMBR), School of Medicine (SoM), Molecular and Medical Research (MMR)Strategic Research Centre, Faculty of Health, Deakin University, Geelong,Pigdons Road, Waurn Ponds, Geelong, Victoria, Victoria 3217, Australia | |
Corresponding author : Professor Jagat Rakesh Kanwar Nanomedicine- Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Molecular and Medical Research (MMR) Strategic Research Centre, Faculty of Health, Deakin University, Geelong, Pigdons Road, Waurn Ponds, Geelong, Victoria, Victoria 3217, Australia Tel: 0061 3 52271148; Fax: 0061 3 52272539 E-mail: jagat.kanwar@deakin.edu.au |
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Received: May 03, 2015 Accepted: June 12, 2015 Published: June 16, 2015 | |
Citation: Chaudhary R, Kanwar RK, Kanwar JR (2015) Zinc Ferrite Nanoparticles as Highly Effective Magnetic Resonance Imaging Contrast Agents with Emphasis on Atherosclerosis. J Nanomater Mol Nanotechnol 4:3. doi:10.4172/2324-8777.1000164 |
Abstract
Zinc Ferrite Nanoparticles as Highly Effective Magnetic Resonance Imaging Contrast Agents with Emphasis on Atherosclerosis
Conventionally and most commonly used commercial contrastagents for magnetic resonance imaging (MRI) diagnostics are based on paramagnetic gadolinium Gd (III) chelates. They have widespread use in cancer and cardiovascular imaging where they are perfused directly into the blood vessel followed by MRI of the diseased tissues. The functional mechanism of electron dense gadolinium complex is by interaction with the surrounding protons and shortening the T1 relaxation time.