Review Article, J Immunodefic Disor Vol: 3 Issue: 1
Vitamin D and HIV Infection: A Systematic Review
Natália Barbosa, Laura Costa*, Mara Pinto, Patrícia Rosinha, Inês Rosinha and Mariana Couto | |
Laboratory of Immunology, Basic and Clinical Immunology Unit, Faculty of Medicine, University of Porto, Portugal | |
Corresponding author : Laura Costa Laboratory of Immunology, Basic and Clinical Immunology Unit, Faculty of Medicine, University of Porto, Al. Prof. Hernâni Monteiro, Porto, 4200-319, Portugal E-mail: laura.a.costa@hotmail.com |
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Received: September 02, 2013 Accepted: February 10, 2014 Published: March 13, 2014 | |
Citation: Barbosa N, Costa L, Pinto M, Rosinha P, Rosinha I, et al. (2014) Vitamin D and HIV Infection: A Systematic Review. J Immunodefic Disor 3:1. doi:10.4172/2324-853X.1000107 |
Abstract
Vitamin D and HIV Infection: A Systematic Review
The Human Immunodeficiency Virus (HIV) infects human T cells, causing a disease that progressively leads to a dramatic deterioration of the immune function. The Acquired Immunodeficiency Syndrome (AIDS) is present when CD4+ cell count is below 200 cells/mm3 or the patient has an opportunist infection, such as esophageal candidiasis or Pneumocystis pneumonia. Since life expectancy of HIV-infected individuals has increased, mostly as a result of advances in diagnosis and treatment, they are more willing to develop long-term chronic complications, some of which have been associated with vitamin D deficiency.