Hepatitis viruses belong to the genus Orthohepadnavirus of the family Hepadnaviridae. It has been found in various animals like (duck, heron, woodchuck, ground squirrel, and primates), These viruses are the leading causes of diseases like chronic liver disease which results in chronic hepatitis, hepatocellular carcinoma and cirrhosis in the world. Hepatitis is an acute self-limiting disease in humans, causing particularly high mortality in pregnant women (HE virus (HEV) is a zoonotic virus, which is transmitted across species between humans, swine, boars, deer, chicken, and rabbits. Journal plays an important role in finding new innovations to find cure, drugs to the diseases by spreading innovative ideas and research to scientific world through research, review articles.