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Hindi Research Article, J Otol Rhinol Vol: 3 Issue: 1
Transfusion of Aged Blood in Head and Neck Free Flap Surgery: Perioperative Outcomes Analysis
| Scott Koepsell1, Mina Le2, Amy Anne Lassig2, Bruce Lindgren3, Claudia Cohn1 and Samir S Khariwala2* |
| 1Division of Transfusion Medicine, Department of Laboratory Medicine and Pathology, University of Minnesota, USA |
| 2Department of Otolaryngology – Head and Neck Surgery, University of Minnesota, USA |
| 3Biostatistics and Bioinformatics Core, Masonic Cancer Center, University of Minnesota, USA |
| Corresponding author : Samir S Khariwala Department of Otolaryngology- Head and Neck Surgery, University of Minnesota, MMC 396, 420 Delaware St SE, Minneapolis, MN, 55455, USA Tel: 612 625 9449; Fax: 612 625 2101 E-mail: Khari001@umn.edu |
| Received: October 23, 2013 Accepted: December 09, 2013 Published: December 15, 2013 |
| Citation: Koepsell S, Le M, Lassig AA, Lindgren B, Cohn C, Khariwala SS (2013) Transfusion of Aged Blood in Head and Neck Free Flap Surgery: Perioperative Outcomes Analysis. J Otol Rhinol 3:1. doi:10.4172/2324-8785.1000140 |
Abstract
Transfusion of Aged Blood in Head and Neck Free Flap Surgery: Perioperative Outcomes Analysis
Background: Transfusion of aged red blood cells (RBCs), those that are near their expiration date, occurs commonly at tertiary medical centers and is associated with decreased tissue oxygenation. Patients who undergo microvascular free tissue reconstruction of the head and neck may be particularly sensitive to old RBCs because the anastomosis and microvasculature of the flap require smooth flow and sufficient blood flow and oxygenation, respectively.
Methods: A retrospective review of clinical and laboratory data in a series of consecutive cases of microvascular reconstruction receiving blood transfusions was performed at a tertiary academic medical center. All patients undergoing ablative surgery of the head and neck with free flap reconstruction between September 2007 and March 2011 were selected. Rates of neck infection, wound dehiscence, free flap loss, need to return to the operating room for revision surgery, infection at the free flap donor site, and mortality were assessed as was age of RBCs transfused preoperatively or postoperatively.
