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Hindi Editorial, J Otol Rhinol Vol: 1 Issue: 1
A Stem Cell-Based Replacement for the Inner Ear
| Zhengqing Hu* |
| Department of Otolaryngology-HNS, Wayne State University School of Medicine, USA |
| Corresponding author : Zhengqing Hu Department of Otolaryngology-HNS, Wayne State University School of Medicine, USA E-mail: zh@med.wayne.edu |
| Received: June 27, 2012 Accepted: June 28, 2012 Published: June 30, 2012 |
| Citation: Hu Z (2012) A Stem Cell-Based Replacement for the Inner Ear. J Otol Rhinol 1:1 doi:10.4172/2324-8785.1000e103 |
Abstract
A Stem Cell-Based Replacement for the Inner Ear
Birds, fish, and other non-mammalian vertebrates can regenerate inner ear hair cells throughout life via two mechanisms; the nonmitotic transdifferentiation of supporting cells, and the mitotic proliferation and differentiation of a subset of supporting cells. A possible third mechanism is that non-mammalian vertebrates may regenerate inner ear hair cells through the differentiation of resident stem cells, but it is still controversial whether stem cells in adult sensory epithelia are from a specialized reserve pool of distinct cell type or from a subtype of supporting cells.
