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Hindi Research Article, J Spine Neurosurg Vol: 2 Issue: 3
Spinal Cord Injury-Induced Discharges Modify the Function of Glutamatergic System and Improve Ground and Skilled Locomotor Control
| Zaghloul Ahmed1,3*, Ahmed Hawash3 and Andrzej Wieraszko2,3 | |
| 1Department of Physical Therapy, The College of Staten Island, Staten Island, NY 10314, and Graduate Center/The City University of New York, New York, NY 10016, USA | |
| 2 Department of Biology, The College of Staten Island, Staten Island, NY 10314, and Graduate Center/The City University of New York, New York, NY 10016, USA | |
| 3The Center for Developmental Neuroscience, The College of Staten Island, Staten Island, New York, NY 10314, USA | |
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Corresponding author : Zaghloul Ahmed |
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| Received: February 22, 2013 Accepted: June 20, 2013 Published: June 24, 2013 | |
| Citation: Ahmed Z, Hawash A, Wieraszko A (2013) Spinal Cord Injury-Induced Discharges Modify the Function of Glutamatergic System and Improve Ground and Skilled Locomotor Control. J Spine Neurosurg 2:3. doi:10.4172/2325-9701.1000115 |
Abstract
Spinal Cord Injury-Induced Discharges Modify the Function of Glutamatergic System and Improve Ground and Skilled Locomotor Control
The injury of the spinal cord evokes intense neuronal activity of the spinal neurons. It has been always assumed that this excessive activity, correlated with a massive release of excitatory neurotransmitter, glutamate would impair functional recovery. This assumption constituted a base for developing many pharmacological treatments for acute spinal cord injury (SCI) aimed at reduction of this hyperactivity.
