Research Article, J Vet Sci Med Diagn Vol: 3 Issue: 3
Sildenafil Efficacy on Renal Ischemia- Reperfusion Injury in Experimental Dogs
Esam Mosbah1, El- Sayed El- Shafaey1, Youssef El- Seady2, Walaa Awadin3* and Adel Zaghloul1 |
1Department of Surgery, Anaesthesiology and Radiology, Mansoura University, Mansoura, Egypt |
2Department of Physiology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt |
3Department of Pathology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt |
Corresponding author : Dr. Walaa Awadin Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt Tel: +201011610725; Fax: +20502379952 E-mail: walaafekriawadin@yahoo.com |
Received: March 24, 2014 Accepted: June 09, 2014 Published: June 13, 2014 |
Citation: Mosbah E, El- Shafaey ES, El- Seady Y, Awadin W, Zaghloul A (2014) Sildenafil Efficacy on Renal Ischemia- Reperfusion Injury in Experimental Dogs. J Vet Sci Med Diagn 3:3. doi:10.4172/2325-9590.1000139 |
Abstract
Sildenafil Efficacy on Renal Ischemia- Reperfusion Injury in Experimental Dogs
The present study reveals a catastrophic corrosive ingestion injury of upper gastrointestinal tract. A 17 year old boy intentionally ingested some corrosive acid and died due to perforation of stomach and peritonitis. The autopsy findings and toxicological analysis report confirmed that he had ingested sulphuric acid. A thorough literature review of corrosive ingestion injuries, their diagnosis and treatment allowed to show the fatality of such cases depend on the type and amount of corrosive ingested, the state of stomach whether empty or full, the promptness of treatment given and various such factors.