Review Article, J Immunol Tech Infect Dis Vol: 2 Issue: 1
RNA Interference: A Recent Approach for the Remedy of Various Diseases
Urkude Vikas*, Shrivastava Rahul, Mishra Amit, Yadav Mahavir and Tiwari Archana | |
School of Biotechnology, Rajiv Gandhi Proudyogiki Vishwavidyalaya, State Technological University of Madhya Pradesh, Bhopal (M.P), India | |
Corresponding author : Urkude Vikas School of Biotechnology, Rajiv Gandhi Proudyogiki Vishwavidyalaya, State Technological University of Madhya Pradesh, Airport Bypass Road, Bhopal-462033, India Tel: 0755742006; Fax: 0755267883 E-mail: vikasurkude@gmail.com |
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Received: January 05, 2013 Accepted: March 13, 2013 Published: March 19, 2013 | |
Citation: Vikas U, Rahul S, Amit M, Mahavir Y, Archana T (2013) RNA Interference: A Recent Approach for the Remedy of Various Diseases. J Immunol Tech Infect Dis 2:1. doi:10.4172/2329-9541.1000105 |
Abstract
RNA Interference: A Recent Approach for the Remedy of Various Diseases
RNA interference (RNAi) has been a recently discovered phenomenon for the analysis of regulation of gene expression in a variety of cells, by which target messenger RNA (mRNA) is cleaved by small interfering complementary RNA (siRNA). The technique is now established in in-vitrosystems, and much work is focussed on adapting RNAi for in vivoapplication. This technology may also be used for therapeutic purposes, functional genomics and target validation. This review will describe the basic biological processes that drive RNAi, indicate current approaches for the treatment of various diseases, and forecast future areas of development.