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Hindi Research Article, J Otol Rhinol Vol: 4 Issue: 1
Relationship of Vitamin D Levels in Thyroid Malignancy
| Matthew Marino1, Andrew M. Hinson1, Eric R. Siegel2, Jonathan W.Rutledge1, Donald L. Bodenner3,4 and Brendan C. Stack Jr.1,4* | |
| 1Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Arkansas, USA | |
| 2Department of Biostatistics, University of Arkansas for Medical Sciences,Arkansas, USA | |
| 3Department of Geriatrics, University of Arkansas for Medical Sciences, Arkansas,USA | |
| 4University of Arkansas for Medical Sciences Thyroid Center, Arkansas, USA | |
| Corresponding author : Brendan C Stack Jr. MD FACS, FACE, 4301 W. Markham St. #543, Little Rock, AR 722135 Tel: 501-686-5140; Fax: 501-686-8029 E-mail: bstack@uams.edu |
|
| Received: May 06, 2014 Accepted: August 10, 2014 Published: January 28, 2014 | |
| Citation: Marino M, Hinson AM, Siegel ER, Rutledge J, Bodenner DL, et al. (2015) Relationship of Vitamin D Levels in Thyroid Malignancy. J Otol Rhinol 4:1. doi:10.4172/2324-8785.1000204 |
Abstract
Relationship of Vitamin D Levels in Thyroid Malignancy
Vitamin D has been reported in several studies to have antiproliferative, anti-apoptotic and pro-differentiating effects in several tumor types. The role of vitamin D in the incidence and/or progression of thyroid malignancy remain largely unknown. We performed a retrospective chart review of postoperative 25-hydroxyvitamin D levels from 255 subjects receiving total (n=197) or completion (n=58) thyroidectomy for benign (n=190) and malignant (n=65) disease at the University of Arkansas for Medical Sciences between October 2005 and July 2013. No significant difference (P = 0.72) was observed between postoperative 25-hydroxyvitamin D levels in subjects with malignant pathology (median 25 ng/mL; range 21-37 ng/ml) versus benign pathology (median 27 ng/ml; range 19.5-35 ng/ml). In our limited study, there was no correlation between postoperative 25-hydroxyvitamin D status and pathological findings in subjects undergoing thyroidectomy.
