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Hindi Research Article, J Spine Neurosurg Vol: 3 Issue: 6
Prognostic Significance of Immunohistochemical Expression of EGFR, Inos and Ki-M1P in Skull Base Chordoma: A Series of 74 Patients
| Akhavan-Sigari R1*, Abili M2, Rohde V1 and Ostertag H3 | |
| 1Department of Neurosurgery, University Medical Center Göttingen, Georg-August-University Göttingen, Germany | |
| 2Department of Neurosurgery, Mashhad University of Medical Sciences, Taleghani Hospital, Mashhad, Iran | |
| 3Department of Pathology, Nordstadt Medical Center, Klinikum Hannover, Germany | |
| Corresponding author : Akhavan-Sigari R University Medical Center Göttingen, Georg-August-University Göttingen, Germany Tel: +49-551-396033; Fax: +49-551-398794 E-mail: reza.akhavan-sigari@med.uni-goettingen.de |
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| Received: June 24, 2014 Accepted: July 30, 2014 Published: August 04, 2014 | |
| Citation: Akhavan-Sigari R, Abili M, Rohde V, Ostertag H (2014) Prognostic Significance of Immunohistochemical Expression of EGFR, Inos and Ki-M1P in Skull Base Chordoma: A Series of 74 Patients. J Spine Neurosurg 3:6 doi:10.4172/2325-9701.1000163 |
Abstract
Prognostic Significance of Immunohistochemical Expression of EGFR, Inos and Ki-M1P in Skull Base Chordoma: A Series of 74 Patients
To investigate the expression of epidermal growth factor receptor (EGFR), inducible nitric oxide synthase iNOS and Ki-M1P in skull base chordoma. To the authors’ knowledge, little is known regarding the prognostic significance of receptor tyrosine kinase and role of iNOS expressed by macrophages in chordoma induced inflammation and tumor progression of skull base chordoma.
