The selective and immunomodulating effect of the proton preparation NSC-631570

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Wassil Nowicky

Nowicky Pharma/Ukrainian Anti-Cancer Institute, Austria

: J Clin Exp Oncol

Abstract

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It is well known that all cells possess the negative charge and cancer cells have a much more negative charge than normal cells. This property has been used for the creation of the anticancer preparation on basis of greater celandine alkaloids with the positive charge. The experiment has been carried out on basis of the sum of greater celandine alkaloids as well as on basis of the pure chelidonine keeping the aim to understand the mechanism of action of the preparation NSC 631570. Chelidonine is the tertiary alkaloid and because of that it doesn’t have the property to fluoresce. After its transformation into the quartet alkaloid, it becomes a proton, accumulates in cancer tumors very fast what is visible thanks to its autofluorescence. Until now this preparation has been tested on over 100 cancer cell lines and on 12 normal cell lines and the results of the studies carried out in more than 120 universities and research centers (in particular at the National Cancer Institute (the USA) have shown that the NSC-631570 killed only cancer cells without having damaged the normal cells what confirmed its selective effect. In clinical trials, it also has proved its anticancer efficacy and caused no noteworthy side effects. The results of in-vitro studies also have shown the direct deletion of cancer cells and its ability to regenerate the immune system. Such a property is unusual for an anticancer agent but as it can be seen that the NSC-631570 possesses some distinct immune properties. In several immune target-effector systems NSC-631570 significant-ly amplified the malignotoxic activity of macrophages, lymphocytes and NK cells, and stimulates dendritic cells maturation in-vitro. While the parameters like B-lymphocytes count, immune globulin concentrations, complement and acute phase proteins did not change significantly, it can be postulated NSC-631570 modulates the cellular part of the immune system whereas the humoral part remains unaffected.

Biography

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Wassil Nowicky, Dipl. Ing., Dr. techn., DDDr. H. C., Director of “Nowicky Pharma” and President of the Ukrainian Anti-Cancer Institute. Has finished his study at the Radiotechnical Faculty of the Technical University of Lviv with the end of 1955 with graduation to “Diplom Ingenieur” in 1960 which title was nostrificated in Austria in 1975. Dr Wassil Nowicky became the very first scientist in the development of the anticancer protonic therapy and is the inventor of the preparation against cancer with a selective effect on basis of celandine alkaloids “NSC-631570”. He used the factor that cancer cells are more negatively charged than normal cells and invented the Celandine alkaloid with a positive charge thanks to which it accumulates in cancer cells very fast. Author of over 300 scientific articles dedicated to cancer research. Dr Wassil Nowicky is a real member of the New York Academy of Sciences, member of the European Union for applied immunology and of the American Association for scientific progress, honorary doctor of the Janka Kupala University in Hrodno, doctor “honoris causa” of the Open international university on complex medicine in Colombo, honorary member of the Austrian Society of a name of Albert Schweizer. He has received the award for merits of the National guild of pharmacists of America. the award of Austrian Society of sanitary, hygiene and public health services and others.

E-mail: dr.nowicky@yahoo.de