The effect of treatment therapy on the levels of specific immunoglobulin-E and calcipherol serum of the patients with allergic rhinitis

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Abdul Qadar Punagi and Stella Fitrianty Attu

Hasanuddin University, Indonesia

: J Otol Rhinol

Abstract

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This research aimed to find out the effect of the treatment therapy of the additional vitamin D on the levels of specific IgE of the patients with allergic rhinitis. This is an experimental research with pre-and post-test design. The research involved 40 patients with allergic rhinitis, who were divided into two groups. Group-1 consisting of 20 patients, treated with intranasal spray Fluticasone therapy and vitamin D of 2400 IU for 21 days and Group-2 consisting of 20 patients were only treated with intranasal spray Fluticasone for 21 days. The levels of the calciferol and IgE of specific Der p of both groups of patients were examined before and after the therapy. The examination of the calciferol and IgE specific Der p was done using ELISA method. From the analysis both groups did not showed any significant difference (p>0.05) based on the gender and age of the patients. The result of Mann-Whitney analysis revealed a significant change difference (p>0.05) between the two groups, that is, the level of IgE specific Der p showed greater decrease in the group receiving vitamin D compared to the group not receiving vitamin D.

Biography

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Abdul Qadar Punagi has his expertise in rhinology and passion in research related nose disease and allergy. He is recently Chairman of Division of Rhinology and Head of Department t of ORL, Hasanuddin University.

E-mail: qa_dar@yahoo.co.id