Interventional Psychiatry-Era of Neurostimulation for Treatment refractory Depression

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Prashant Gajwani

University of Texas at Houston, USA

: J Spine Neurosurg

Abstract

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Major Depressive Disorder affects 16% of population and is one of the most disabling illness of our times. There are many pharmacological and psychotherapeutic interventions available. However, despite advances in treatment, 1/3 rd of patients suffering from depression progress to treatment refractory state where in they do not get any benefit from conventional treatment modalities. US FDA has approved several neuromudulation treatments such as Electro-convulsive treatment (ECT), Vagus nerve stimulation (VNS) and TMS (transcranial magnetic stimulation). Recently deep Brain Stimulation (DBS) has become an experimental treatment available for patients failing to respond to ECT. DBS can be used for conditions for which neural circuitry has been developed. Our center is exploring Median Forebrain Bundle (MFB) as possible target for DBS for treatment refractory depression.

Biography

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