Association of HbA1c level with pregnancy outcome in GDM patients in 3rd trimester

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Faryal Mustary, Ferdousi Begum

Woman and Child Hospital, Bangladesh
BIRDEM Hospital, Bangladesh

: Androl Gynecol: Curr Res

Abstract

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Background: GDM is a special endocrine complication of the gestational period. HbA1c is a variety of hemoglobin of which synthesis rate is positively related to the glucose concentration of RBC and HbA1c can reflect the mean blood glucose level within the past 8 to 10 weeks.

Method: This prospective observational study was conducted in the Department of Obstetrics and Gynaecology in BIRDEM Hospital, Dhaka over a period of one year. A total of 90 GDM women in the 3rd trimester of pregnancy were enrolled in this study. Maternal complications in the antenatal period, during labor, post-partum period and fetal outcome were studied in both controlled and uncontrolled HbA1c.

Results: In this study, the mean age of the GDM patients was 27.17 ± 4.63 years varied from 20 to 40 years. Regarding maternal antepartum complications,Vulvovaginitis (26.7% vs 4.4%), UTI (17.8% vs 4.4%) and preterm delivery (24.4% vs 6.7%) were found significantly higher in uncontrolled HbA1c than controlled HbA1c. It was observed that LUCS (68.9% vs 37.8 %) was significantly higher in the uncontrolled groups than in the controlled groups. About the intrapartum complications, complete perineal tear (21.4% vs 0.0 %) was significantly higher in uncontrolled than controlled HbA1c group. UTI (28.6% vs 3.6 %) was the statistically significant postpartum complication of the mother who delivered vaginally. Regarding neonatal outcome, RDS (12.8% vs 0.0 %) showed a significant difference between the two groups.

Conclusion: HbA1c is a useful marker to predict pregnancy outcomes in GDM patients.

Biography

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Faryal Mustary has completed her MS in Gynaecology & Obstetrics from Dhaka University. Now she is an Associate consultant, Gynae & Obs department in Woman and Child Hospital, Uttara (National Health Care Network), Bangladesh Diabetic Association. She is certified in diabetologist (CCD, Birdem), trained in infertility management and IUI. She also trained in colposcopy and cervical pathology. She has published two papers in reputed BIRDEM Medical Journals (Vol-9) and has been serving as a member of OGSB (obs gynae society Bangladesh).

E-mail: dr.faryalsaroare@gmail.com