AMNIOTIC MEMBRANE - NOVEL APPROACH FOR WOUND HEALING

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Meenakshi Chauhan

University of Health Sciences, India

: J Regen Med

Abstract

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Background: The management of gaped wounds is a great challenge for the surgeons. Human amnion is a readily available and cost effective dressing material for these gaped wounds. Aims: The present study was carried out to study the efficacy of human amnion in gaped wounds following various obstetric and gynecological surgeries. Settings and design: A prospective and comparative study conducted in the department of obstetrics and gynecology at a tertiary care centre in North India. Methods and Material: Sixty patients with wound gaping were randomly allocated into 2 groups, group A (n-30) had wound dressing with human amnion after taking consent and group B (n-30) had conventional dressing with normal saline, betadene. Statistical analysis: Chi square test and Fisher exact test Results: Majority of patients (57.5%) had wound gaping after emergency cesarean section. Out of 30 patients in group A, epithelialization and healthy granulation tissue was observed in majority of the patients (17 patients) after 2 amnion dressings (4 days) whereas in group B, these changes were observed in majority of the patients (21 patients) after 8 days. Hence resuturing was done in majority of the patients after 4 days and 8 days in group A and B respectively (p value <0.001). Wound depth was markedly minimized in 20 out of 30 patients in group A making resuturing very easy and none in group B (p value <0.001). Conclusion: Human amnion is a readily available, cheap and highly effective dressing material for gaped wounds.

Biography

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