Perspective, J Pharm Sci Emerg Drugs Vol: 11 Issue: 1
The Importane of Inhalation Dosage Forms in Respiratory Drug Delivery
Ritshu Kimora*
Department of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka, Japan
*Corresponding Author: Ritshu Kimora
Department of Pharmaceutical Sciences
University of Shizuoka, Suruga-ku, Shizuoka, Japan
E-mail: kimorar@shizuoka.jp
Received date: 22 January, 2023, Manuscript No. JPSED-23-95083; Editor assigned date: 24 January, 2023, Pre QC. JPSED-23-95083(PQ);Reviewed date: 15 February, 2023, QC No. JPSED-23-95083; Revised date: 21 February, 2023, Manuscript No. JPSED-23-95083(R); Published date: 28 February, 2023, DOI: 10.4172/2324-8955.1000126.
Citation: Kimora R (2023) he Importane of Inhalation Dosage Forms in Respiratory Drug Deli ery . J Pharm Sci Emerg Drugs 11:1.
Description
Inhalation is an important dosage form for respiratory drugs that delivers medications directly to the lungs. It is a highly effective method for treating respiratory disorders such as asthma, Chronic Obstructive Pulmonary Disease (COPD), and cystic fibrosis.
The inhalation route of drug delivery is preferred over oral or parenteral routes for respiratory drugs due to several advantages. Inhalation ensures a rapid onset of action, direct delivery of medication to the lungs, and minimizes systemic side effects. It also provides a higher concentration of drug to the target site and reduces the dose required for therapeutic effect.
Inhalation dosage forms include Metered-Dose Inhalers (MDIs), Dry Powder Inhalers (DPIs), and nebulizers. MDIs are the most commonly used inhalation devices, which use propellants to deliver the medication in aerosol form. DPIs, on the other hand, deliver the medication in dry powder form without the need for propellants. Nebulizers deliver the medication in a fine mist form and are mostly used for severe respiratory disorders.
Inhalation is an important dosage form for various respiratory drugs, including bronchodilators, corticosteroids, and antibiotics. Bronchodilators are drugs that relax the airway smooth muscles, which help in widening the airways and improving airflow. They are used to treat conditions such as asthma and COPD. Corticosteroids are anti-inflammatory drugs that help reduce swelling and inflammation in the airways. They are used to treat conditions such as asthma and allergic rhinitis. Antibiotics are drugs that help in treating respiratory infections caused by bacteria.
Inhalation dosage forms advantages over other dosage forms for respiratory drugs
Rapid onset of action: Inhalation delivers the medication directly to the lungs, resulting in a rapid onset of action. This is particularly important for drugs that need to act quickly, such as bronchodilators for acute asthma attacks.
Targeted drug delivery: Inhalation delivers the medication directly to the lungs, providing a higher concentration of drug to the target site. This reduces the dose required for therapeutic effect and minimizes systemic side effects.
Improved patient compliance: Inhalation dosage forms are easy to use and do not require the patient to swallow a pill or receive an injection, which improves patient compliance.
Reduced side effects: Inhalation dosage forms deliver the medication directly to the lungs, minimizing systemic side effects. This is particularly important for corticosteroids, which can cause systemic side effects when taken orally.
Portable and convenient: Inhalation devices are portable and convenient, allowing patients to take their medication with them wherever they go. This improves patient adherence to treatment.
However, inhalation dosage forms also have some disadvantages. The main disadvantage is that they require proper technique for effective drug delivery. Patients need to be trained on how to use inhalation devices correctly to ensure proper drug delivery. Improper use of inhalation devices can result in reduced drug delivery and inadequate treatment.
Conclusion
Inhalation is a highly effective dosage form for respiratory drugs that delivers medication directly to the lungs, providing many advantages over other dosage forms. Inhalation devices, such as MDIs, DPIs, and nebulizers, are commonly used to treat respiratory disorders such as asthma, COPD, and cystic fibrosis. Inhalation ensures a rapid onset of action, direct delivery of medication to the lungs, and minimizes systemic side effects. However, proper training on inhalation device technique is crucial for effective drug delivery and optimal treatment outcomes. Overall, inhalation is an important and valuable tool in the management of respiratory disorders.