Research Article, J Immunol Tech Infect Dis Vol: 5 Issue: 4
Mathematical Model on Avian Influenza with Quarantine and Vaccination
Bimal Kumar Mishra1* and Durgesh Nandini Sinha2 | |
1Department of Mathematics, Birla Institute of Technology, Mesra, Ranchi-835215, India | |
2Department of Mathematics, Temple University, Philadelphia, PA USA | |
Corresponding author : Bimal Kumar Mishra Department of Mathematics, Birla Institute of Technology, Mesra, Ranchi-835215, India E-mail: drbimalmishra@gmail.com |
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Received: October 05, 2016 Accepted: November 02, 2016 Published: November 07, 2016 | |
Citation: Mishra BK, Sinha DN (2016) A Mathematical Model on Avian Influenza with Quarantine and Vaccination. J Immunol Tech Infect Dis 5:4. doi: 10.4172/2329-9541.1000152 |
Abstract
Avian influenza virus poses risks to both bird and human population. In primary strain, mutation increases the infectiousness of avian influenza. A mathematical model of Avian Influenza for both human and bird population is formulated. We have computed the basic reproduction number and for both human and bird population respectively and we prove that the model is locally and globally asymptotically stable for disease-free equilibrium point when and . We also prove that the unique endemic equilibrium point is globally asymptotically stable in bird population when . Extensive numerical simulations and sensitivity analysis for various parameters of the model are carried out. The effect of Vaccination and Quarantined class with Recovered class are critically analyzed.