Correlation of vitamin D with HbA1c in CAD diabetic and non CAD diabetic patients in India

Vitamin D deficiency is a major concern across the globe. Evidence indicates that vitamin D supplementation can improve health condition in several diseases including diabetes. The objective is to find out the correlation of vitamin D with HbA1c in Coronary Artery Disease (CAD) diabetic and non CAD diabetic patients in northern India. This is a cross-sectional study conducted in the Department of Medicine and Department of Biochemistry, Maulana Azad Medical College, New Delhi, India and included 324 type-2 Diabetes Mellitus (T2DM) patients of age 50 years and above who have a history of diabetes for more than five years. Patients who were already taking vitamin D supplements were excluded from this study. Patients were equally divided into two groups. Group-1: CAD diabetic (N=162), group-2: Non CAD diabetic (N=162). Height, weight, BMI, waist circumference, Vitamin D was measured in all patients. SPSS software was used to analyze the data. The correlation coefficient was calculated in both groups with respect to vitamin D and HbA1c. An inverse relation has been observed in CAD Diabetic (r value -0.0794) and non CAD diabetic (r value -0.011) when it was compared with vitamin D values. In our study, we found that patients having higher vitamin D levels have better glycemic control and have lower HbA1c values. Therefore, vitamin D supplementation can improve glycemic control in diabetic population.