Research Article, Androl Gynecol Curr Res Vol: 2 Issue: 4
Metformin Exposure in Early Pregnancy and Spontaneous Abortions in Women with Polycystic Ovary Syndrome
Finn F. Lauszus*, Mette Viftrup-Lund and Melina Gade |
Department of Gynecology and Obstetrics, Herning Hospital, Denmark |
Corresponding author : Finn Lauszus, PhD, MD Associate Professor, Research Specialist, Gynecology Department, Herning Hospital, Gl Landevej 61, DK- 7400 Herning, Denmark Tel:+4578434614; Fax: +4578434636; E-mail: finlau@rm.dk |
Received: May 20, 2014 Accepted: September 20, 2014 Published: September 25, 2014 |
Citation: Lauszus FF, Viftrup-Lund M, Gade M (2014) Metformin Exposure in Early Pregnancy and Spontaneous Abortions in Women with Polycystic Ovary Syndrome. Androl Gynecol: Curr Res 2:4. doi: 10.4172/2327-4360.1000128 |
Abstract
Metformin Exposure in Early Pregnancy and Spontaneous Abortions in Women with Polycystic Ovary Syndrome
We sought to determine whether metformin affects the rate of first trimester spontaneous abortions and congenital malformations in women with PCOS. Design. Consecutive series of metformin treated women with a questionnaire followup. Setting. Department of Gynecology and Obstetrics at Herning and Holstebro Hospital. Population. 117 women with PCOS treated with metformin prior to and during early pregnancy.