Liver is the primary organ for the detoxification, as well as being the target of many of environmental chemicals. Most common liver diseases are caused by a combination of environmental factors and genetic background. Inherited diseases are the genetic disorders of liver. More than 100 liver diseases are genetically inherited. Some disease symptoms may be present in parents; other parents may have no symptoms, but their children may have the disease. Hereditary hemochromatosis is the most common genetic liver disorder. This section discusses new concepts in the genetics and inherited liver diseases with disease pathogenesis and novel therapeutic options. Hepatocytes are metabolic super-achievers in the body which play critical role in synthesizing molecules. Hepatocytes house many different metabolic pathways. The major metabolic functions of the liver are Carbohydrate Metabolism, Fat Metabolism and Protein Metabolism. The role of the liver in metabolism is very crucial for processing a number of compounds as they move through the body. The Journal of Liver: Disease & Transplantation addresses both the liver pathology and liver transplantation. JLDT stands among the liver journals in the globe. The major areas of journal include advances in liver diseases, liver trauma, portal hypertension and pediatric liver tumors. Journal of Liver: Disease & Transplantation focuses on the topics hepatitis, cirrhosis, liver cancer, alcohol damage, fatty liver, metabolic and genetic liver diseases, autoimmune liver diseases, liver transplantation and techniques, surgical complications and transplantation outcomes. The Journal is using quality and standard peer review process with help of Editorial and review board members for its paper publications. It is also using online manuscript submission and manuscript tracking systems.