Cell Biology: Research & TherapyISSN: 2324-9293

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Special Issue Article, Cell Biol Res Ther S Vol: 0 Issue: 0

Isolation and Characterization of Stem Cells Sub Population within the Human Fetal Liver

Shaik Mahaboob Vali1, Sandeep kumar Vishwakarma1, Avinash Bardia1, Santosh K Tiwari1, G. Srinivas2, Avinash Raj2, Chaturvedula Tripura2, Pratibha Nallari3, Md. Aejaz Habeeb1, Gopal Pande2 and Aleem A Khan1*
1Centre for Liver Research and Diagnostics, Deccan College of Medical Sciences, Owaisi Hospital, Kanchanbagh, Hyderabad, Andhra Pradesh, India
1Centre for Cellular and Molecular Biology, Hyderabad, Andhra Pradesh, India
3Department of Genetics, Osmania University, Hyderabad, Andhra Pradesh, India
Corresponding author : Dr. Aleem A Khan
Associate Professor, Centre for Liver Research and Diagnostics, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad-500 058, Andhra Pradesh, India.
Tel: +91-040-24342954
E-mail: aleem_a_khan@rediffmail.com
Received: January 02, 2014 Accepted: March 24, 2014 Published: March 28, 2014
Citation: Vali SM, Vishwakarma SK, Bardia A, Tiwari SK, et al., (2014) Isolation and Characterization of Stem Cells Sub Population within the Human Fetal Liver. Cell Biol: Res Ther S1:006 doi:10.4172/2324-9293.S1-006

Abstract

Isolation and Characterization of Stem Cells Sub Populationwithin the Human Fetal Liver

Human fetal liver is the potential source of both hematopoietic and non-hematopoietic stem cells which can be identified using phenotypic markers. Isolation of homogenous populations of hepatic progenitor cells and their sub-populations is an essential prerequisite for investigating specific markers and appropriate cell types for their possible clinical applications. Several studies have demonstrated the presence of a variety of stem cell populations within the fetal liver. The present study was undertaken to identify specialized cell populations, their valuable growth potential and bi-potential differentiation capability derived from human fetal liver using CD133.

Keywords: Human hepatic progenitor cells; CD133, Sub-population; Coexpression

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