Primary immunodeficiency can be treated by preventing and treating infections, treating the underlying cause of the immune problem and boosting the immune system. Primary immune disorders in some cases might be linked an autoimmune disorder or cancer where the associtaded illness should be treated first. The infections in the patients can be managed by antibiotics and treating symptoms. Infections are typically treated with antibiotics but in some cases hospitalization and treatment with intravenous antibiotics might be necessary when the infections don’t respond to standard medications. Medications can also be used to relieve symptoms such pain, fever, sinus congestion. Immune system can also be boosted by Gamma interferon therapy, Immunoglobulin therapy, Growth factors therapy. Stem cell transplantation has been proved to offer a permanent cure for several forms of life-threatening immunodeficiency. In this therapy, normal stem cells are transferred to the immunodeficienct person that renders them a normally functioning immune system. There is no cure for AIDS but treatments are available to manage symptoms that can improve the quality and length of life. Antiretroviral therapy suppresses the HIV virus replication in the body. A combination of antiretroviral drugs, called highly active antiretroviral therapy (HAART), is very effective in reducing the amount of HIV in the bloodstream.