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Hindi Research Article, J Genet Disor Genet Rep Vol: 2 Issue: 2
Genotype-phenotype characteristics of β thalassemia children in the Gaza Strip, Palestine
| Maged M Yassin 1, Mahmoud M Sirdah2*, Rami M Al Haddad3, Abdel-Monem H. Lubbad2 and Mansour S Al-Yazji2 | |
| 1Faculty of Medicine, Islamic University of Gaza, Palestine | |
| 2Biology Department, Al Azhar University-Gaza, Palestine | |
| 3Palestinian Thalassaemia and Haemophilia Centre, Palestine Avenir Foundation, Gaza, Palestine |
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| Corresponding author : Dr. Mahmoud Sirdah Biology Department, Al Azhar University-Gaza, PO Box 1277, Gaza, Palestine Tel: +97 05 99 481194; Fax: +97 082641888 E mail: msirdah@hotmail.com; sirdah@alazhar.edu.ps |
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| Received: November 11, 2013 Accepted: December 17, 2013 Published: December 23, 2013 | |
| Citation: Yassin M M, Sirdah M M, Al Haddad R M, Lubbad A H, Al-Yazji M S (2013) Genotype-phenotype characteristics of β thalassemia children in the Gaza Strip, Palestine. J Genet Disor Genet Rep 2:2. doi:10.4172/2327-5790.1000109 |
Abstract
Genotype-phenotype characteristics of β thalassemia children in the Gaza Strip, Palestine
Thalassemias are considered one of the most common known hereditary blood disorders in mankind, quantitatively affecting the synthesis of human hemoglobin. At least 60,000 severely affected individuals are born every year. Thalassemias have been encountered in practically every racial group and geographic location in the world; however, they are most common among individuals originating from tropical and subtropical regions. Thalassemias are classified based on the particular globin chain(s) that are produced in a reduced amount, so the main types of this inherited disorder which have been defined are α, β, δβ, δ, γδ β, and εγδβ thalassemias.
