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Hindi Research Article, Mol Med Ther Vol: 1 Issue: 2
Genome-Scale Mapping of MicroRNA Signatures in Human Embryonic Stem Cell Neurogenesis
| Xuejun H. Parsons1,2*, James F. Parsons1,2 and Dennis A. Moore1,2 |
| 1San Diego Regenerative Medicine Institute, San Diego, CA 92109, USA |
| 2Xcelthera, San Diego, CA 92109, USA |
| Corresponding author : Dr. Xuejun H. Parsons San Diego Regenerative Medicine Institute, San Diego, CA 92109, USA E-mail: parsons@SDRMI.org |
| Received: September 18, 2012 Accepted: November 20, 2012 Published: December 10, 2012 |
| Citation: Parsons XH, Parsons JF, Moore1 DA (2012) Genome-Scale Mapping of MicroRNA Signatures in Human Embryonic Stem Cell Neurogenesis. Mol Med Ther 1:2. doi:10.4172/2324-8769.1000105 |
Abstract
Genome-Scale Mapping of MicroRNA Signatures in Human Embryonic Stem Cell Neurogenesis
To date, lacking of a clinically-suitable source of engraftable human stem/progenitor cells with adequate neurogenic potential has been the major setback in developing effective cell-based therapies against a wide range of neurological disorders. Derivation of human embryonic stem cells (hESCs) provides a powerful tool to investigate the molecular controls in human embryonic neurogenesis as well as an unlimited source to generate the diversity of human neuronal cell types in the developing CNS for repair.