Metabolic Diseases/Digestive Disease occurs when some organs do not function normally due to a hormone or enzyme deficiency. Digestive system comprises of various organs that transforms food into essential nutrients and removes the waste material out of the body. Digestive system is pivotal to maintain good health because of that the body is able to nourish itself. The largest structure of digestive system is GI tract and the diseases that are related to the GI tract are designated as digestive diseases. Digestive Disease includes the diseases of the oesophagus, stomach, spleen, liver, gall bladder, small intestine, large intestine, colon, and rectum. Most widely known disease of the digestive system is colon cancer. There are many diseases and conditions related to the digestive system that are chronic and difficult to diagnose which includes irritable bowel syndrome, lactose intolerance, GERD, celiac disease, peptic ulcer.