Journal of Immunodeficiency & DisordersISSN: 2324-853X

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Research Article, J Immunodefic Disor Vol: 3 Issue: 1

Evidence of the Human T-cell Lymphotropic Virus (HTLV-I) Circulation in Santiago De Cuba Province (Cuba)

Dayamí Martin1, Dervel F Díaz1, Onelvis Isaac2, Liuber Y Machado1*, Dania Romay1 and Héctor M Díaz1
1AIDS Research Laboratory, Carretera Tapaste y Autopista Nacional, San José de las Lajas, Mayabeque, Cuba
2Banco de Sangre Provincial Renato Guitar, Santiago de Cuba, Cuba
Corresponding author : Liuber Y Machado
AIDS Research Laboratory, Carretera Tapaste y Autopista Nacional, San José de las Lajas, Mayabeque, Cuba
Tel: 047-848729
E-mail: cicdc@infomed.sld.cu
Received: July 05, 2013 Accepted: December 02, 2013 Published: December 10, 2013
Citation: Martin D, Díaz DF, Isaac O, Machado LY, Romay D, et al,. (2014) Evidence of the Human T-cell Lymphotropic Virus (HTLV-I) Circulation in Santiago De Cuba Province (Cuba). J Immunodefic Disor 3:1. doi:10.4172/2324-853X.1000106

Abstract

Evidence of the Human T-cell Lymphotropic Virus (HTLV-I) Circulation in Santiago De Cuba Province (Cuba)

Human adult T-cell leukaemia and the HTLV-associated myelopathy/tropical spastic paraparesis constitute the indicative main disease of the HTLV-I virus circulation in endemic areas. The objective of this work was to confirm the existence or not of the HTLVI infection in Santiago de Cuba Province where there have not been reported any HTLV seropositive persons up to the present. We studied 1548 sera samples: 1436 blood donors, 35 transfused patients and 77 persons with clinical symptoms associated to this virus. We used enzyme-linked immunosorbent (EIA) and Western blot assays (DAVIH-BLOT HTLV-I (DAVIH Laboratories, Cuba) to detect and confirm the HTLV-I-specific antibodies.

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