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Hindi Research Article, J Immunodefic Disor Vol: 1 Issue: 2
Evaluation of Growth and Bone Metabolism in Adolescent Patients with Common Variable Immunodeficiency
| Necil Kutukculer*, Damla Goksen, Nesrin Gulez, Neslihan E. Karaca, Guzide Aksu and Sukran Darcan |
| Department of Pediatrics, Ege University, Izmir, Turkey |
| Corresponding author : Necil Kutukculer Department of Pediatrics, Ege University, Izmir, Turkey E-mail: necil.kutukculer@ege.edu.tra |
| Received: June 20, 2012 Accepted: August 06, 2012 Published: August 12, 2012 |
| Citation: Lee BK (2012) Addiction: A Runaway Phenomenon of Our Time? J Addict Behav Ther Rehabil 1:1 doi:10.4172/2324-853X.1000101 |
Abstract
Evaluation of Growth and Bone Metabolism in Adolescent Patients with Common Variable Immunodeficiency
Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency, resulting in increased susceptibility to infections and diminished responses to protein and polysaccharide vaccines. Most common infections are sinopulmonary caused by Streptococcus pneumonia, Haemophilus influenza, Klebsiella pneumonia and sometimes mycoplasma. An intrinsic B cell defect; inability to differentiate to plasma cells and secrete immunoglobulins, has been most commonly observed in terms of pathogenesis. Many defects in T cells have also been noted in patients with CVID.