Biography
Dr. Gentile is a recognized expert in the transglutaminase research area and has a strong background in the molecular biology and biochemical aspects of the transglutaminase (TG) enzymes expression, activity and function. His work has been focused to the tTG (TG2) characterization in normal and pathological cellular events (cell growth and differentiation, adhesion, apoptosis) by molecular biology, immunological and biochemical studies.
Research Interest
Cloning and characterisation of the gene for human tissue transglutaminase.
Transfection of the human tissue transglutaminase cDNA in Balb-C 3T3 mouse fibroblasts: molecular and cellular characterisation of the stable transfected cell lines.
Site direct mutagenesis of the human tissue transglutaminase cDNA.
Characterisation of rat intestinal transglutaminase and studies on transglutaminase-mediated modifications of gliadins in relation to the Coeliac Disease.
Characterization of the human tissue transglutaminase as a mediator of the cell signal transduction pathway.
Studies on the possible involvement of transglutaminases in the pathogenesis of neurodegenerative diseases.
Identification and characterisation of a transglutaminase variant from rat Nervous System and human neuroblastoma cells.
Related Publications
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Marburg Virus Disease: A Review Literature
Review Article: J Genes Proteins 2017, 1:1
DOI:
Sajida Sboui and Ahmed Tabbabi
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Antibacterial Mechanism of Bacteriolyses of Bacterial Cell Walls by Zinc(ââ¦Â¡) Ion Induced Activations of PGN Autolysins, and DNA damages
Research Article: J Genes Proteins 2017, 1:1
DOI:
Ishida T
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Comparison of the Hypoproteinemic Capacities of Erythropoietin and U-74389G
Research Article: J Genes Proteins 2017, 1:1
DOI:
Τsompos C, Panoulis C, Τοutouzas K, Triantafyllou A, Ζografos CG and Papalois A
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Metagenomics Prospective in Bio-mining The Microbial Enzymes
Review Article: J Genes Proteins 2017, 1:1
DOI:
Santosh Thapa, Hui Li, Joshua O'Hair, Sarabjit Bhatti and Suping Zhou
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DNA Barcoding of Freshwater Prawn Species of Two Genera Macrobrachium and Caridina Using mt-COI Gene
Research Article: J Genes Proteins 2017, 1:1
DOI:
Udayasuriyan R, Saravana Bhavan P and Kalpana R