Computational Biology is a scientific field that involves the development of various methods, mathematical modeling and computational simulation techniques to the study of biological system and behavior. Bioinformatics is a combination of two scientific branches, i.e. computer science and biology. It involves application of computer science, applied mathematics, statistics, biochemistry, chemistry, biophysics, molecular biology, genetics, genomics, ecology, evolution, neuroscience, and visualization. Computational Biology is a branch similar to Bioinformatics and involves common tools like Java, C#, XML, Perl, C, C++, Python etc to develop algorithms. Journal of Applied Bioinformatics & Computational Biology receives vast number of computational biology manuscripts under its regular quarterly issue keeping a track record of the latest research & study in the computational biology field. The journal holds wide scope and relevance under computational biology. The journal works on the hybrid model under which authors can freely submit research/review/case reports/commentaries etc as subscription or open access article as per the requirements and feasibility.