Heart failure is a clinical syndrome with the symptoms and signs which suggest impairment of the heart as a pump supporting physiological circulation. Heart failure is caused by structural or functional abnormalities in heart. The objective evidence of these abnormalities is necessary for the diagnosis of heart failure. The major symptoms includes are breathlessness, fatigue and ankle swelling. Signs in heart failure could be due to pulmonary and systemic congestion, the structural abnormalities causing heart failure, the structural abnormalities resulting from heart failure, or from complications of therapy. Initially, research into heart failure concentrated on patients with heart failure and reduced contraction of the left ventricle. Consequently, therapeutic interventions were tested in this group of patients. The agreed description of this group of patients is heart failure with left ventricular systolic dysfunction (LVSD). Over the last 10 years it has become evident that almost half the patients with heart failure syndrome do not have LVSD. This group has several definitions and names given to their condition. Since patients with LVSD are defined on the basis of their reduced left ventricular ejection fraction, the Guideline Development Group (GDG) elected to adopt the term heart failure with preserved ejection fraction (HFPEF) to describe patients with heart failure and no evidence of LVSD. There is no single diagnostic test for heart failure, and diagnosis relies on a combination of history, physical examination & relevantinvestigations International Journal of Cardiovascular Research emerges as a best journal with impact factor compared to other competitive journals focusing chronic heart failure and other cardiology studies by bringing up the recent research to global scientific community through its publications. The papers submitted are undergone through perfect plagiarism checks, later peer reviewed by the expert group and published after through revisions.