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+44 28 3718 0055Journal of Genetic Disorders & Genetic ReportsISSN: 2327-5790
Sebastiano Calandra Author
Subjects of specialization
Affiliation
Glomerular lipoprotein thrombi
Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Biography
Sebastiano Calandra belongs to Department of Biomedical, Metabolic and Neural Sciences intrested in the field Lipoprotein glomerulopathy (LPG); APOE gene mutation; Dominant inheritance with incomplete penetrance; Glomerular lipoprotein thrombi; Hyperlipidemia from University of Modena and Reggio Emilia, Modena, Italy
Publications
Research Article Open Access
Lipoprotein Glomerulopathy: Molecular Characterization of Three Italian Patients and Literature Survey
Author(s): Antonio Pasquariello, Livia Pisciotta, Tiziana Sampietro, Giovanna Pasquariello, Pellegrino Masiello, Matilde Masini, Francesco Sbrana, Mariarita Puntoni, Roberto Miccoli, Sebastiano Calandra and Stefano Bertolini
Lipoprotein Glomerulopathy: Molecular Characterization of Three Italian Patients and Literature Survey
Lipoprotein glomerulopathy (LPG) is a rare kidney disease, mainly reported in Asian subjects, linked with rare APOE gene mutations resulting in a structurally abnormal Apolipoprotein E (ApoE), the plasma accumulation of lipoprotein remnants and the formation of lipid thrombi in glomerular capillaries. This study reports the molecular characterization of three unrelated Italian patients with long standing LPG.
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