Dr. Madani attended undergraduate and medical school at the University of Florida. After graduation from medical school in 2001, she completed residency training at the University of Florida in 2005, and subsequently joined the faculty. She is a Board Certified Fellow of the American College of Obstetrics and Gynecology and an active member of the Association of Professors of Gynecology and Obstetrics.Dr. Madani is part of an integrated team of MIS physicians that is dedicated to providing safe, effective, minimally invasive gynecological care. Dr. Madani's clinical practice includes general obstetrics and general and surgical gynecology. She has a special interest in minimally invasive surgery, urogynecology, and advanced laparoscopy. She is a certified da Vinci robotic surgeon.

Shireen Madani Sims research and professional interests include medical education as well as medical and surgical gynecology and clinical interests include Pelvic laparoscopy,Pregnancy care, Urogynecology, and Women's health.