Biography
Dr. Pamela Norton is an associate professor in the Department of Microbiology & Immunology at Drexel University College of Medicine, and associate director of the Drexel Institute for Biotechnology and Virology Research. Dr. Norton received his Ph.D. from Tufts University in 1986. Dr. Norton lab members are investigating the causes and consequences of hyperfucosylation of many liver-derived glycoproteins that appear in the circulation of individuals with HCC. A second HCC-related change in glycosylation is an increase in the production of highly branched structures in tumor but not nearby non-tumor tissue. The roles of these altered glycoforms are as yet poorly understood, but they represent potentially important biomarkers for early detection of disease.
Research Interest
Dr. Norton research interests inculde Development of novel antiviral drugs for use against hepatitis B virus (HBV) infection; characterization of biomarkers for hepatocellular carcinoma.
Publications
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Proteomic Perspectives on Viral Infections: Insights into Pathogenesis and Therapeutic Targets
Perspective: J Virol Antivir Res
DOI:
Yasuhiro Ishida