Dr. Fried is studying patients with chronic hepatitis C in order to investigate the effects of alcohol consumption on disease progression. The underlying hypothesis is that alcohol accelerates the rate of liver fibrosis in hepatitis-infected livers through multiple mechanisms that can be individually measured in the laboratory. Studies will determine if chronic alcohol intake enhances the activation of Kupffer cells that increase inflammation of the liver. His studies provide new hope in the treatment of alcohol-related diseases.

Management of viral hepatitis and chronic liver disease