Denise is the Chief Sleep Scientist for Eastern Health and is an Adjunct Research Fellow in the Faculty of Medicine, Nursing & Health Sciences at Monash University. She is a current Board Director of the Thoracic Society of Australia and New Zealand.

Denise's research program focuses on the cardio-metabolic consequences of sleep apnoea, and its subsequent treatment, in the settings of obesity, aging and ethnicity, Sleep and sleep disorders, Sleep disorders, cardiovascular control, arousal from sleep