Use Of FIBERGRAFT BG Morsels Mixed With BMA In Anterior Cervical Discectomy And Fusion At 1, 2, 3 And 4 Levels: A Retrospective Analysis Of Fusion Results

Background: Fibergraft material is a synthetic bone graft substitute that has been proven in animal models to reveal 100% fusion in posterolateral spine fusion at 26 weeks. The purpose of this study is to analyze post-op CT scans to evaluate the fusion effectiveness of Fibergraft BG Morsels when combined with bone marrow aspirate (BMA) in one-, two-, three-, and four-level anterior cervical discectomy and fusion (ACDF).

 Methods: In this retrospective, single-center medical record review, post-op cervical CT scans at approximately six months were evaluated in 27 patients by one senior orthopedic spine surgeon. The surgeon was blinded to the clinical outcomes, patient demographics and past medical history. Fusion results were given a grade of either I, II, III or IV based on the presence of trabecular bridging bone across both graft-vertebral body interfaces.

 Results: A total of 52 levels were grafted in the 27 subjects who underwent the Smith-Robinson anterior cervical discectomy and fusion. 88.5% of the levels were classified as Grade I complete fusion, 5.8% of the levels classified as Grade II, 3.8% classified as Grade III, and 1.9% classified as Grade IV.

Conclusions: Fibergraft BG Morsels mixed with bone marrow aspirate (BA) is an effective bone graft option in one-, two-, three-, and four-level ACDF procedures. This synthetic bioactive glass bone graft substitute combined with BMA achieves high rates of fusion comparable to the biological performance of autologous bone graft.