Trimethoprim Associated with Pathological Food Refusal: A Case Report

Trimethoprim Associated with Pathological Food Refusal: A Case Report

Trimethoprim is an anti-bacterial agent, generally accepted as safe in children. We describe three children with pathological food refusal. All three used trimethoprim as antibiotic prophylaxis. After cessation of trimethoprim the feeding problems resolved and nasogastric feeding was no longer necessary, thereby indicating a probable association.