Trends and Profile of Ovarian Cancer at a Medical Institute

Trends and Profile of Ovarian Cancer at a Medical Institute

Ovarian cancer ranks fifth amongst cancers in women in industrialized countries, lowest rates from developing countries as well as Japan, and highest from Scandinavian countries have been reported. Present study was done to know trends, profiles of cases with ovarian cancer in eastern part of Maharashtra province of India. Over 3 decades, 10388 cancer cases were diagnosed. Of all cancers in women which were 52.23% of cancers in men and women, 46.15% were gynaecological. Ovarian cancer (472) contributed to 8.70% cancers in women, 18.85% of gynaecological cancers, third highest position after cervical, breast cancers, 4.47% cancers in women, 8.39% gynaecological cancers between 1982– 1986 and 13.05% cancers in women and 23.83 % gynaecological cancers between 2007- 2011. Of 472 ovarian cancer cases, 168(35.60%) were between 35-49 years, 56 (11.86%) above 65 years. Between 1982 to 1986 (called Block A), 8.3% and 50% and between 2007 to 2011 (called Block F), 16.59 % and 31.44% cases were between 20-34 years and 50-64 years respectively (two tailed P value 0.0116, by Fischer exact test) significant difference. No woman was above 65 years in Block A, but 17.02% in Block F. Between 1982-90, there was no nullipara, but women with five or more births decreased from 41.66% in Block A, 24.67% in Block F. In Block A 91.66 % and in Block F 37.55% women had not used any contraceptive, 8.33% women in Block A and 49.34% in Block F had undergone tubectomy. Overall number of cases using contraception and sterilization has increased in general population also. Postmenopausal women with ovarian cancer decreased 50% in Block A, 31.44% in Block F. Eleven women (5%) with ovarian cancer never had a pregnancy but none had received fertility inducing drugs. Eight (3.23%) women had family history of ovarian and/or breast cancer. Ovarian cancer occurs even in poor young women with many children. More research is needed for knowing high risk population.