The Functions of Helicobacter pylori Metalloprotease in Gastric Disease

Helicobacter pylori, a Gram-negative bacterium, infects the gastric mucosa of humans and is strongly associated with various gastrointestinal diseases, including gastritis, peptic ulcers, and gastric cancer. This article focuses on a specific virulence factor of H. pylori, the metalloprotease gene, and explores its role in the pathogenesis of gastric diseases. Understanding the mechanisms by which this gene contributes to H. pylori-induced gastric damage is crucial for developing targeted therapeutic interventions and preventive strategies