The Effects of High-Fat or High-Carbohydrate Diet on Intramyocellular Lipids

The Effects of High-Fat or High-Carbohydrate Diet on Intramyocellular Lipids

Aim: High-fat and high-carbohydrate (carb) diets have been widely consumed over the past few decades; however, the longterm metabolic effects of these diets are unclear. We analysed the effects of a high-fat or high-carb diet on intramyocellular lipids (IMCL), plasma lipids, glycaemia and insulinaemia. Methods: Prospective, randomized, interventional crossover study; 22 overweight women were randomised to two different diet sequences in two phases: weight maintenance and weight loss. IMCL were measured by 1H magnetic resonance spectroscopy.