The aging lung face to COVID-19

Coronavirus disease 2019 (COVID-19) has so far killed many people; with the majority of deaths occurring in people over the age of 65 years. It has been noted that the severity and outcome of COVID-19 depends in part on the patient’s age. The combination of three factors could explain this ascertainment: the first is linked the lung aging, the second is the associated comorbidities in elderly subjects and the third is the particularities of COVID-19. Here we emphasize the modifications linked to pulmonary aging and their role in worsening the COVID-19 disease.