Specificity of the Cardiocerebral-Event Reductions in the Kyoto Heart and Jikei Heart Study

Specificity of the Cardiocerebral-Event Reductions in the Kyoto Heart and Jikei Heart Study

The Kyoto Heart Study was a prospective randomized open blinded end-point (PROBE)-design trial, in which 3031 Japanese patients (mean, 66 years) with uncontrolled hypertension were randomized to either valsartan add-on or non-angiotensin receptor blocker (ARB) treatment.