RNA Interference: A Recent Approach for the Remedy of Various Diseases

RNA Interference: A Recent Approach for the Remedy of Various Diseases

RNA interference (RNAi) has been a recently discovered phenomenon for the analysis of regulation of gene expression in a variety of cells, by which target messenger RNA (mRNA) is cleaved by small interfering complementary RNA (siRNA). The technique is now established in in-vitrosystems, and much work is focussed on adapting RNAi for in vivoapplication. This technology may also be used for therapeutic purposes, functional genomics and target validation. This review will describe the basic biological processes that drive RNAi, indicate current approaches for the treatment of various diseases, and forecast future areas of development.