Repair of Nasal Septal Perforation with Porcine Small Intestinal Submucosa Xenograft

Repair of Nasal Septal Perforation with Porcine Small Intestinal Submucosa Xenograft

Numerous techniques have been described for nasal septal perforation repair, with various degrees of success in achieving closure. Evidence supports the use of bilateral mucoperichondrial advancement flaps with interpositional grafting for greatest success. Many surgeons use autografts such as fascia, cartilage, bone, and pericranium, however, extracellular matrices have also become popular. We analyze factors determining the success of nasal septal perforations repaired using an acellular, freeze-dried interpositional xenograft derived from Porcine Small Intestinal Submucosa (PSIS).