Preventive Effects of Methanolic Extract of Seeds of Nigella sativa Linn. on PMA Induced Apoptosis in Human Blood Lymphocytess

Although radiation therapy is widely used for cancer-treatment but it is associated with several side effects. It involves free radical/PKC mediated pathway to induce DNA damage and apoptosis in target cells. The tyrosine kinase inhibitors, antioxidants and PKC inhibitors have been reported to be radio-protective. However, new radio-protector, especially from herbal origin is always in demand, as they have comparatively lesser side effects, because of their natural origin.