Plasma Cell Mucositis Affecting Oral Mucosa: Report of 11 Cases and Review of Literature

Plasma cell mucositis is a rare idiopathic inflammatory condition showing benign plasma cell proliferation with erythematous mucosa and varying surface appearances affecting oral, upper respiratory and genital mucosae. Final diagnosis should be achieved by clinicopathological correlation following exclusion of other similarly presenting diseases. Different treatment modalities such as steroids, calcinurin inhibitors, cryotherapy, laser and surgical excision have been used but with varying response. Therefore Plasma cell mucositis presents a challenge in both diagnosis and treatment. Here, we report eleven new cases of plasma cell mucositis and discuss their histological variations and management.