Multimodal Imaging of Atypical Acute Posterior Multifocal Placoid Pigment Epitheliopathy

We present a 52 years-old woman who developed acute posterior multifocal placoid pigment epitheliopathy (APMPPE) with atypical features. APMPPE was unilateral and associated with serous retinal detachment and disc edema causing severe vision loss to 20/400. Oral corticosteroid therapy was prescribed with rapid resolution of lesions and visual improvement to 20/20. Clinical course and multimodal imaging in illustrating different features provide us clues for the definitive diagnosis.