MRS Chronicles: Navigating the Intricacies of Melkersson-Rosenthal Syndrome

Melkersson-Rosenthal Syndrome is an uncommon condition characterized by orofacial edema, facial nerve palsy, and tongue furrowing. The etiology of this condition is uncertain. Corticosteroids, such as intralesional triamcinolone acetonide, are the principal therapy choices for orofacial edema, offering only symptomatic relief. In circumstances when triamcinolone acetonide is not accessible, intralesional betamethasone and oral doxycycline can be used. This thorough review article seeks to improve understanding of Melkersson-Rosenthal syndrome among healthcare professionals, researchers, and those afflicted by the illness. It addresses the many management options used in the treatment of this unusual condition, focusing on the difficulties in diagnosis and management.

Keywords: Facial Palsy, Facial Edema, Lip Edema, Orofacial Granulomatosis, Recurrent Facial Palsy, Fissured Tongue, Lingua Plicata